{"id":1122,"date":"2026-01-05T10:41:56","date_gmt":"2026-01-05T10:41:56","guid":{"rendered":"https:\/\/wickedsister.evit.com.au\/index.php\/2026\/01\/05\/breakthrough-again\/"},"modified":"2026-01-05T10:41:56","modified_gmt":"2026-01-05T10:41:56","slug":"breakthrough-again","status":"publish","type":"post","link":"https:\/\/wickedsister.evit.com.au\/index.php\/2026\/01\/05\/breakthrough-again\/","title":{"rendered":"Breakthrough Again"},"content":{"rendered":"<div class=\"twitter-share\"><a href=\"https:\/\/twitter.com\/intent\/tweet?url=https%3A%2F%2Fmultiple-sclerosis-research.org%2F2026%2F01%2Fbreakthrough-again%2F&#038;via=the_MSBlog\" class=\"twitter-share-button\" data-size=\"large\">Tweet<\/a><\/div>\n<p>I was asked what I thought of the MS in the media report.<\/p>\n<p>&#8220;Two new subtypes of MS found in \u2018exciting\u2019 breakthrough&#8230;Scientists have discovered two new subtypes of\u00a0 MS paving the way personalised treatments and better outcomes for patients&#8221;<\/p>\n<p>I choose not to comment on these papers becuase of the agro it causes, but you know what I think about P for predict from imaging and neurofilament studies&#8230;they are good a suggesting what may happen at a population level but at the individual level I have not been impressed of the correlations&#8230;but here artifical intelligence can make a breakthrough of those with early neurofilament loss verse those with most likely hood of worsening or early deficit great.<\/p>\n<\/p>\n<p>This is the paper is &#8220;Willard C, Puglisi L, Ravi D, Dmitrieva M, Mattiesing RM, Barkhof F, Alexander DC, Harlow DE, Piani-Meier D, Eshaghi A. Combined magnetic resonance imaging and serum analysis reveals distinct multiple sclerosis types. Brain. 2025;148(12):4578-4591. doi: 10.1093\/brain\/awaf331. PMID: 41325776;<\/p>\n<p><em>Source: <a href=\"https:\/\/multiple-sclerosis-research.org\/2026\/01\/breakthrough-again\/?utm_source=rss&#038;utm_medium=rss&#038;utm_campaign=breakthrough-again\" rel=\"nofollow noopener\" target=\"_blank\">multiple-sclerosis-research.org<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tweet I was asked what I thought of the MS in the media report. &#8220;Two new subtypes of MS found in \u2018exciting\u2019 breakthrough&#8230;Scientists have discovered two new subtypes of\u00a0 MS paving the way personalised treatments and better outcomes for patients&#8221; I choose not to comment on these papers becuase of the agro it causes, but&#8230;<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[11,15,9,8,13,14,12,10],"class_list":["post-1122","post","type-post","status-publish","format-standard","hentry","category-multiple-sclerosis-research","tag-brain-repair","tag-marburg-type-ms","tag-ms","tag-multiple-sclerosis","tag-myelin","tag-neuroregeneration","tag-oligodendrocyte","tag-remyelination"],"_links":{"self":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts\/1122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/comments?post=1122"}],"version-history":[{"count":0,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts\/1122\/revisions"}],"wp:attachment":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/media?parent=1122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/categories?post=1122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/tags?post=1122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}