{"id":1581,"date":"2026-03-12T12:00:20","date_gmt":"2026-03-12T12:00:20","guid":{"rendered":"https:\/\/wickedsister.evit.com.au\/index.php\/2026\/03\/12\/brain-volume-loss-may-not-reflect-disability-in-progressive-ms\/"},"modified":"2026-03-12T12:00:20","modified_gmt":"2026-03-12T12:00:20","slug":"brain-volume-loss-may-not-reflect-disability-in-progressive-ms","status":"publish","type":"post","link":"https:\/\/wickedsister.evit.com.au\/index.php\/2026\/03\/12\/brain-volume-loss-may-not-reflect-disability-in-progressive-ms\/","title":{"rendered":"Brain volume loss may not reflect disability in progressive MS"},"content":{"rendered":"<p><a href=\"https:\/\/multiplesclerosisnewstoday.com\/news-posts\/2026\/03\/12\/brain-volume-loss-disability-progressive-ms\/\" title=\"Brain volume loss may not reflect disability in progressive MS\" rel=\"nofollow\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"551\" src=\"https:\/\/multiplesclerosisnewstoday.com\/wp-content\/uploads\/2026\/01\/iStock-2211224275-800x551.jpg\" class=\"webfeedsFeaturedVisual wp-post-image\" alt=\"An image shows pieces of a brain flying away.\" style=\"margin: auto;margin-bottom: 15px;max-width: 100%\" data-wp-pid=\"159564\" \/><\/a><\/p>\n<p>Loss of brain volume (brain atrophy), a measure often used in clinical trials to track disease progression, may not accurately reflect worsening disability in people with primary progressive multiple sclerosis (PPMS). That\u2019s according to a new analysis of data from the Phase 3 PROMISE trial, in which measures of brain atrophy were only poorly associated [&#8230;]<\/p>\n<p>The post <a href=\"https:\/\/multiplesclerosisnewstoday.com\/news-posts\/2026\/03\/12\/brain-volume-loss-disability-progressive-ms\/\">Brain volume loss may not reflect disability in progressive MS<\/a> appeared first on <a href=\"https:\/\/multiplesclerosisnewstoday.com\">Multiple Sclerosis News Today<\/a>.<\/p>\n<p><em>Source: <a href=\"https:\/\/multiplesclerosisnewstoday.com\/news-posts\/2026\/03\/12\/brain-volume-loss-disability-progressive-ms\/\" rel=\"nofollow noopener\" target=\"_blank\">multiplesclerosisnewstoday.com<\/a><\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Loss of brain volume (brain atrophy), a measure often used in clinical trials to track disease progression, may not accurately reflect worsening disability in people with primary progressive multiple sclerosis (PPMS). That\u2019s according to a new analysis of data from the Phase 3 PROMISE trial, in which measures of brain atrophy were only poorly associated&#8230;<\/p>\n","protected":false},"author":0,"featured_media":1582,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[11,15,9,8,13,14,12,10],"class_list":["post-1581","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-multiple-sclerosis-research","tag-brain-repair","tag-marburg-type-ms","tag-ms","tag-multiple-sclerosis","tag-myelin","tag-neuroregeneration","tag-oligodendrocyte","tag-remyelination"],"_links":{"self":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts\/1581","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/comments?post=1581"}],"version-history":[{"count":0,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/posts\/1581\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/media\/1582"}],"wp:attachment":[{"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/media?parent=1581"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/categories?post=1581"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wickedsister.evit.com.au\/index.php\/wp-json\/wp\/v2\/tags?post=1581"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}