I’ve built myself a little quiet life since retiring and going on disability in 2022. It exists on a shoestring with my days spent doing crosswords while listening to music and enjoying various drinks. It’s what I’ve begun to refer to as a still life. Much like many a famous painting hanging on the wall…
What Makes B cells return..Should we be Worried?
Tweet As you know I get drawn to studies related to things we have been doing and treatment failure due to anti-drug antibodies is on thing they can also result in faster B cell repopulation. But what other things do we know. Well quite a few things like, Age, BMI, Number of Doses, Frequency of…
Are antibodies always bad news?
Tweet Answer is probably not Morris-Downes MM, Smith PA, Rundle JL, Piddlesden SJ, Baker D, Pham-Dinh D, Heijmans N, Amor S. Pathological and regulatory effects of anti-myelin antibodies in experimental allergic encephalomyelitis in mice. J Neuroimmunol. 2002;125(1-2):114-24. Neurological deficit in experimental allergic encephalomyelitis (EAE) and multiple sclerosis (MS) is probably a consequence of synergy between…
Bike MS in Texas – largest of events in US – raises over $9M for research, care
More than 5,000 cyclists took part in the 2026 Bike MS: ACC Texas MS 150 event, a two-day fundraising ride with proceeds aiming to support research and services for people with multiple sclerosis (MS). Part of the Bike MS initiative, the Texas ride is the largest fundraising cycling event in the U.S. Held at the…
Consortium of Multiple Sclerosis Centers
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Protecting My Peace: Small Habits That Help Me Navigate Life with MS
By Nicole Robinson Living with multiple sclerosis has taught me a lot, especially when it comes to protecting my mental and emotional well-being. When I was first diagnosed, I didn’t have it all together. There were moments of confusion, frustration, and … Continue reading → Source: blog.mymsaa.org
B cell repopulation
Tweet This looks at repopulation after depletion and I have to say if finds what others find in definining characteristics associated which repopulation e.g. younger age etc Marefi A, Grasso EA, Garber L, Narula S, Waldman A, Bar-Or A, Banwell B, Hopkins SE. Factors Influencing Early and Late B-Cell Repopulation After Rituximab Therapy in Paediatric…
Tampons could offer way to monitor multiple sclerosis nerve damage
Menstrual fluid collected from tampons could one day provide a simple, noninvasive way to measure a biomarker of nerve damage and potentially track disease activity in neurological conditions such as multiple sclerosis (MS). Researchers at Nextgen Jane, in collaboration with Siemens Healthineers, found that neurofilament light chain (NfL) — a protein released when nerve cells are…
Life with MS is hard, but you don’t have to figure it out on your own
Between my tours with the Army, a new course was added to the curriculum for me to teach — a two-week basic combat skills course for support personnel. The logic was that if a mechanic or cook attached to a special forces team overseas ever had to do something outside of his or her skill…
Phase 2 pegsebrenatide trial begins dosing in progressive MS
The first participant has been dosed in an investigator-initiated Phase 2 clinical trial testing Neuraly‘s experimental medication pegsebrenatide as a potential treatment for progressive forms of multiple sclerosis (MS). Called TAG-MS (NCT07497399), the study is being led by Ellen Mowry, MD, at Johns Hopkins University in Maryland, with additional clinical sites expected to participate. The…