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CMSC 2026: Peer support app may boost confidence after MS diagnosis

An app-based, one-to-one peer support program from Shift.ms that connects people newly diagnosed with multiple sclerosis (MS) with someone more experienced may help them feel more confident in managing their condition, with self-reported psychological benefits for both people in the pairing. That’s according to five-year…

Abnormal fat in brain immune cells may help drive progressive MS

Abnormal fat buildup inside the brain’s immune cells may help to drive neurological damage and disability progression in people with progressive forms of multiple sclerosis (MS), a study found. The findings also point to a possible therapeutic target. Researchers showed that blocking an enzyme called…

Chris Pero – MSAA’s June 2026 Artist of the Month

MSAA features the work of many talented artists affected by multiple sclerosis as part of our annual MSAA Art Showcase. Each month we share these artists’ inspiring stories and beautiful artwork with you as our Artist of the Month. This month, we celebrate Chris Pero as June’s … Continue reading → Source:…

CMSC 2026: Trial data show frexalimab benefits lasting 3 years

Three years of treatment with Sanofi’s investigational antibody therapy frexalimab was associated with persistently low disease activity and no new safety concerns in people with relapsing forms of multiple sclerosis (MS). That’s according to new data from an ongoing open-label extension phase of a global…

Anti-CD20 antibodies. Know One, Know them All?

Tweet This is a question I have posed and answered. Are they the same? You know that you can have them as an infusion or at home and they inhibit relapses and new lesion formation and this class of drug has become one of the…

It’s WorldMSDay again, and…

Tweet …there’s plenty of declarations of good will, compassion, energy to solve problems related to MS – that’s all great and laudable. However, I can’t stop thinking there are some elephants in the room that keep getting ignored since people tend to jump on the…

PIRA, PIRMA, RAW, MAW is it SH1-In, SH1-Out? We need to target different processes to those targeting relapses to limit disability progression

Tweet Tur C. High-efficacy therapy and progression independent of relapse and MRI activity in multiple sclerosis. Brain. 2026:awag175. https://doi.org/10.1093/brain/awag175 They say “The main mechanism through which patients with multiple sclerosis (MS) acquire disability is progression independent of relapse activity (PIRA)” (Yep a widely held view)…..”However,…

&2@!* What does this mean for progression

Tweet No disrespect to the authours here, but when I read the title of the paper I asked what the flip does this mean? What is the Era of PIRA-A. This is an MDPI journal and so is a pay to publish site so you…

Learning to let it go

I had a terrible and embarrassing experience within the last week. I can’t even believe I’m gonna write about it it’s embarrassing but that’s what this site is for. This experience definitely falls under the dark category in the travails of Bethy Bright and Dark.…