Tweet The are some people that believe that MS is caused by EBV and there are some of then that think there are EBVvariants that cause MS. Now i can buy the former view but as to the latter view I say where is the evidence, you just have to read to see that people…
Cladribine inhibits CNS inflammation…NSS!
Tweet Cladribine enters the CNS and about 25% of the levels in the blood reach the brain and so active levels of cladribine can enter the CNS. In this study they say “Regarding OCBs status, OCBs disappeared in five patients while they were detected in two patients (A total of 39 gave repeat samples) who…
What is Vidofludimus?
Tweet Although it sounds like a character out of Gladiator III….Vidofludimus (calcium) is not a Russel Crowe look alike…but it is a teriflunomide look alike. It is not a generic of teriflunomide but works in the same way. Teriflunomide is the active breakdown product of leflunomide which is used in rheumatoid arthritus. So would leflunomide…
ProfG with the rallying call
Tweet Giovannoni G, Payne O, Valero-Hernández E, Kang AS, Kaur Singh B, Baker D, Harris K, Cutino-Moguel T, James LK, Bloom BM. Post-streptococcal Autoimmunity and Its Relevance to Epstein-Barr virus as the Potential Cause of Multiple Sclerosis. J Infect Dis. 2026 Feb 12:jiag035. Source: multiple-sclerosis-research.org
ACTRIMS 2026: ULTIMATE trial testing Briumvi in kids with MS to launch soon
A clinical trial testing TG Therapeutics‘ CD20 inhibitor Briumvi (ublituximab-xiiy) in children with relapsing forms of multiple sclerosis (MS) will begin enrolling participants within the next few months, the developer announced, also unveiling details of the study’s design. The upcoming Phase 2/3 trial (NCT07220252) will run in two parallel parts. A Phase 2 portion called…
Guest Voice: An insurance denial spurs me into advocacy mode
It took exactly 14 days for my health insurance to pick the first fight with me this year. The letter arrived quietly, the way these things always do. Denied. Out of network. This time it was Octave Bioscience’s Multiple Sclerosis Disease Activity (MSDA) test, a blood test that evaluates biomarkers to show what’s happening beneath…
Connecting with Kindness and Compassion
Kindness is something we encounter more often than we realize. At some point, each of us has been at the receiving end of someone’s patience, and those moments stay with us. When we choose to be kind, we keep that … Continue reading → Source: blog.mymsaa.org
ACTRIMS 2026: Vidofludimus calcium targets key MS mechanisms, data show
Immunic Therapeutics‘ experimental oral therapy vidofludimus calcium can target key mechanisms underlying disease progression in multiple sclerosis (MS), including acute and chronic inflammation, as well as Epstein-Barr virus (EBV) reactivation, according to new trial data. The Phase 2 CALLIPER trial (NCT05054140) investigated vidofludimus calcium against a placebo in people with progressive forms of MS. Immunic presented…
MS makes sleep difficult — and sleep studies, too
Like many of my peers in the military, I developed the ability to fall asleep in any position or place and at any time that I wasn’t actively engaged in something. On one occasion, during a particularly loud and turbulent flight, I managed to stay awake just long enough to see an Air Force loadmaster…
MS-Related Pain
It has been close to 25 years since I was diagnosed with Multiple Sclerosis. Over the years, I have learned so much that I wish I didn’t know. Living with Multiple Sclerosis comes with too many unexpected and unpredictable issues. Still, these are all issues one must learn to accept and deal with because they are not going away. I remember…