Navigating the Slow Climb: Our Journey with PPMS Living with Primary Progressive Multiple Sclerosis (PPMS) can often feel like we are navigating a different world than our peers with relapsing forms of the disease. While many in the MS community … Continue reading → Source: blog.mymsaa.org
Physical exercise may help reduce inflammation in MS, study suggests
Physical exercise may help reduce inflammation in multiple sclerosis (MS) by changing the activity of immune T-cells, a new study reports. Findings suggest this effect may depend in part on signaling through the vagus nerve, which connects the brain to other organs and helps regulate automatic bodily functions. Study explores how exercise may affect immune…
MS and pelvic floor dysfunction: What to know
Pelvic floor dysfunction is a common but often overlooked part of living with MS, affecting bladder, bowel, and sexual function. Understanding the signs and working with your care team can help you explore treatments and daily strategies to better manage symptoms. The post MS and pelvic floor dysfunction: What to know appeared first on Multiple…
Wearing Off Effect of Natalizumab..Back to the Drawing Board
Tweet This is an editorial by Afzal S, Conway DS. The wearing-off effect with natalizumab: Back to the drawing board. Neurotherapeutics. 2026;23:e00903. To the paper Freeman SA, Rual C, Biotti D, Lepetit M, Le Berre J, Ferrara K, Treiner E, Ciron J. No association between the wearing-off effect and α4-integrin receptor saturation in natalizumab treated…
MS & weight loss: A different kind of progress
The slightly worn and curled piece of paper asks, “How is what you’re doing going to get you closer to where you want to go?” Dan taped this makeshift sign to the wall of our dining room a few days before his hernia surgery on January 22. He intended to motivate us for his recovery…
Natalizumab assays not quite the same
Tweet Sandoz v Biogen for the use of Natalizumab in MS….What do you go for?….Well we heard last week that neuros on the pharma payroll tend to go with the people giving the lolly. But the companies also do stuff to support the use of their drugs and on of them is JC virus testing….
MS: musings from inside the neurology department waiting room, 21 years later
No one is ever ready to hear what the stranger in front of them has to say. A neurologist examines your MRI and cerebrospinal fluid test results, gazing and thinking. Do they wonder how they will tell you that from this moment on, your life will change—that you’ll need to adapt your lifestyle to include…
MS affects your Brain Networks
Tweet WTF is this? Yep today we are talking a new language and it is one of brain anatomy. The White matter of the brain looks white and contains the axons with their fatty myelin sheath. The grey matter on the outside of the brain and inside of the spinal cord contains the nerve cell…
Bladder problems in MS may lower quality of life by fueling loneliness
Urinary issues are a frequent and distressing reality for women with multiple sclerosis (MS), and new research suggests these symptoms may diminish quality of life, specifically by fueling feelings of loneliness. While the physical burden of bladder dysfunction is well-documented, this study highlights a critical emotional link, suggesting that clinical care must address the social…
EBV antibodies Good or Bad?
Tweet Mendelian randomisation is a research method that uses genetic variation as a natural experiment to test whether a relationship between a risk factor and an outcome is causal rather than just a correlation…in other words it is a cheap way of generating loads of papers for not alot of effort:-). There have been studies…