Immunic Therapeutics‘ experimental oral therapy vidofludimus calcium can target key mechanisms underlying disease progression in multiple sclerosis (MS), including acute and chronic inflammation, as well as Epstein-Barr virus (EBV) reactivation, according to new trial data. The Phase 2 CALLIPER trial (NCT05054140) investigated vidofludimus calcium against a placebo in people with progressive forms of MS. Immunic presented…
MS makes sleep difficult — and sleep studies, too
Like many of my peers in the military, I developed the ability to fall asleep in any position or place and at any time that I wasn’t actively engaged in something. On one occasion, during a particularly loud and turbulent flight, I managed to stay awake just long enough to see an Air Force loadmaster…
MS-Related Pain
It has been close to 25 years since I was diagnosed with Multiple Sclerosis. Over the years, I have learned so much that I wish I didn’t know. Living with Multiple Sclerosis comes with too many unexpected and unpredictable issues. Still, these are all issues one must learn to accept and deal with because they are not going away. I remember…
ACTRIMS 2026: Current exercise habits linked to lower disability in MS: Study
People with multiple sclerosis (MS) who engage in more physical activity tend to have less severe physical and cognitive disability, a study demonstrated. While past exercise levels showed no correlation with later disease onset or slower disability accumulation, current exercise habits were significantly associated with physical disability in MS participants. This association was strongest among…
AcTrims 2026. Can you have MS without EBV infection?
Tweet You get EBV infection before MS in the US army study proof that EBV is the cause of MS…let’s get vaccinating but can you get MS before EBV infection indicating EBV is not the cause of MS. This study looks at Canadians and says yep there are cases before detected EBV infection. They find…
Dan’s healing: Three inches that changed our caregiving choreography
Three inches is roughly the width of a standard smartphone. Not a big deal, right? Sure, three inches is somewhat insignificant, that is, until you start talking about surgery and a caregiving relationship. It. Is. Monumental. That’s the length of the incision across my lower abdomen. A permanent mark left behind by inguinal hernia surgery…
Living with MS pain, the uninvited guest you can’t turn away
Pain and I are well acquainted. I would not go so far as to say we are friends, but we do see each other every day. It isn’t always first thing in the morning; sometimes it’s midafternoon, right after I think to myself, “Wow, pain hasn’t shown up at my doorstep today.” Or it arrives…
ACTRIMS 2026: Bazedoxifene fails to boost myelin repair in women with MS
Bazedoxifene, a medication that alters the activity of the sex hormone estrogen, was safe and well-tolerated but did not promote myelin repair in women with multiple sclerosis (MS) in a Phase 2 clinical trial. The findings come from the ReWRAP study (NCT04002934) and were presented last week at the Americas Committee for Treatment and Research…
ACTRIMS 2026: New study questions whether EBV precedes every MS case
A Canadian study is challenging the growing belief that previous infection with the Epstein-Barr virus (EBV) is necessary for multiple sclerosis (MS) to develop. The findings suggest the virus may not precede every MS case. Using public health insurance claims data, the researchers found a small group of people whose MS-related diagnostic claims appeared before…
Cuando la fortaleza dificulta acercarse a los demás
La fortaleza y la autosuficiencia suelen considerarse como una medalla de honor. Para muchas personas, especialmente aquellas que viven con enfermedades crónicas o incertidumbre constante, la fortaleza se vuelve sinónimo de supervivencia. Nos permite superar días difíciles, pero a menudo … Continue reading → Source: blog.mymsaa.org