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Barriers to Treatment

Tweet Surely number one is avoiding..idiot neuro Snider L, Rodriguez E, Rains H, Peraza H, Montalvo M, Rempe T. Factors associated with delays in multiple sclerosis disease-modifying therapy initiation. Mult Scler J Exp Transl Clin. 2026;12:20552173261447996. doi: 10.1177/20552173261447996. PMID: 42112096; PMCID: PMC13153518. Background: In multiple sclerosis…

New AI partnership targets earlier MS diagnosis using circular RNA

Decode Health and Circular Genomics are partnering to use artificial intelligence (AI) to identify patterns in circular RNA — stable genetic molecules able to signal disease — that may help diagnose multiple sclerosis (MS) earlier and monitor its progression over time. The collaboration brings together…

Ocrevus (ocrelizumab) for multiple sclerosis

Ocrevus (ocrelizumab) is an infusion therapy approved to treat adults with relapsing forms of MS and primary progressive MS. Administered via an intravenous infusion, the treatment is used to reduce the frequency of relapses, lower the number of lesions, and slow disability progression. The post…

Privosegtor optic neuritis clinical trial design gains FDA agreement

The U.S. Food and Drug Administration (FDA) has formally agreed that the design and planned analysis of an upcoming Phase 3 trial testing privosegtor in people with optic neuritis could support a future application seeking the therapy’s approval if the trial succeeds. Optic neuritis, or…

Most of progression is due to the effects of lesions controlled by drugs that inhibit relapses

Tweet Signori A, Montobbio N, Bovis F, Ponzano M, Schiavetti I, Krenn A, Sormani MP. Uncoupling Relapse Reduction and Disability Progression: Evidence From Tolebrutinib Studies. Neurol Clin Pract. 2026; 16:e200612. Objectives: The aim of this study was to evaluate whether the treatment effects of tolebrutinib on…

Life Beyond the Relapse: Real Stories of Living with SPMS

If you are living with secondary progressive multiple sclerosis (SPMS), you know that life feels different from how it used to be. For years, you might have lived in the RRMS world, waiting for an attack, treating it, and mostly … Continue reading → Source:…

A still life

I’ve built myself a little quiet life since retiring and going on disability in 2022. It exists on a shoestring with my days spent doing crosswords while listening to music and enjoying various drinks. It’s what I’ve begun to refer to as a still life.…

What Makes B cells return..Should we be Worried?

Tweet As you know I get drawn to studies related to things we have been doing and treatment failure due to anti-drug antibodies is on thing they can also result in faster B cell repopulation. But what other things do we know. Well quite a…