Tweet ProfK is a CladLad and has been flying the flag for many years. I put this paper up as it reinforces what I was saying about breaks after anti-CD20. Someone asked me if we will ever get a chemical B cell depleters. My answer…
Tweet Hear it from the pulpit, on this occasion set up at The Royal Society: Disclosure (from today’s blogger): Professor Coles chairs the DMEC of ChariotMS (NCT04695080), a trial of cladribine in people with advanced MS, which is supported by the MS Society as part…
When Jennifer and I launched the podcast for A Couple Takes on MS, we hoped it would spark honest conversations about life with Multiple Sclerosis, caregiving, advocacy, and marriage. We did not expect it to become such an important part of our lives. Now, more…
Keep your kitchen cool this Memorial Day weekend with some simple side dish options requiring zero cooking or grilling. These fresh, colorful side dishes take less than 10 minutes to whip up and bring a bright crunch to your holiday … Continue reading → Source:…
Using psychoactive drugs such as alcohol, caffeine, nicotine, cannabis, or opioids may help ease certain symptoms of multiple sclerosis (MS) — but many of these substances can make other MS symptoms worse, a study found. The researchers also found that the specific symptoms a patient…
Tweet Schoof LG, Hogenboom L, van Kempen ZL, Killestein J, van Oosten BW, Strijbis EM. Reinitiating ocrelizumab with a full 600 mg dose after extended treatment interruption: No increased risk of infusion-related reactions. Mult Scler J Exp Transl Clin. 2026 May 15;12(2):20552173261449688. You can get infusion…
In a column I wrote a couple years ago, I noted that, despite my fascination with the subject of psychology, I have only an amateur understanding of it. We can add artificial intelligence (AI) to the long list of things I’m not an expert on.…
The two main mouse models used to study myelin damage in multiple sclerosis (MS) each replicate important but distinct biological features of the disease — but both fall short of capturing its full biological complexity, a new study shows. The findings suggest that each of…
Enrollment is half complete in an ongoing clinical study at Massachusetts General Hospital (MGH) testing whether a PET imaging tracer can reliably measure myelin damage in people with multiple sclerosis (MS). The Phase 1 study (NCT04699747) is recruiting about 60 people — healthy adults and MS…
Tweet Many years ago the new target for MS was reported and it was called RASGRP2. People then wanted to inhibit responses to this protein to treat MS…I thought the idea was a crock and I said this to one of the leading authors of…