Un equip internacional de recerca ha identificat un mecanisme clau que explica per què, en l’esclerosi múltiple (EM), no només es danya la mielina sinó que també moren neurones del cervell. La troballa aporta una nova perspectiva sobre la malaltia i obre la porta a tractaments enfocats a protegir directament les cèl·lules nervioses. La recerca…
La reparació de la mielina podria estar en un gen d’animals d’alta muntanya
Un equip de científics ha identificat un mecanisme biològic inesperat que podria ajudar a reparar la mielina, la capa protectora dels nervis que es veu danyada en l’esclerosi múltiple (EM). La descoberta prové de l’estudi d’animals d’alta muntanya com els iacs, que han desenvolupat adaptacions genètiques per sobreviure en entorns amb poc oxigen. Aquestes adaptacions…
Antibodies in CNS inhibited by natalizumab, What does this tell us about antibodies?
Tweet It says to me the antibodies in the CNS are inpart generated by the peripheral immune system entering the CNS as natalizumab blocks cells entering the inflammed CNS Background: Cerebrospinal fluid (CSF) kappa free light chains (KFLC) is a sensitive marker of intrathecal immunoglobulin synthesis and is incorporated into the 2024 McDonald criteria for multiple…
How a support group opened my eyes to the reality of invisible illness
I don’t remember much about the support group meeting that changed everything. I don’t remember the facilitator’s name, the other people’s faces, how long we sat there, or what anyone actually said. What I remember is the moment, somewhere in the middle of someone else’s story, when I looked around the room and the thought…
Singing for Wellness
By Stacie Prada Last year, my naturopath suggested I take deep breaths each day, and I agreed it would be good for me. I approached it like a prescription and made sure to do it. I followed guided meditations, and … Continue reading → Source: blog.mymsaa.org
EU experts back tolebrutinib approval for SPMS patients with no relapses
Regulators in the European Union are recommendeding that tolebrutinib be approved as a treatment for people with secondary progressive multiple sclerosis (SPMS) who have not experienced a relapse in the last two years. That new positive opinion was issued by the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP), a regulatory body…
11 minutes, 1,900 seats, and not 1 for me: when accessible seating feels anything but accessible
Concert tickets might sound like a small thing, but for Dan and me, they’re not. Live music is one of our favorite ways to feel connected, normal, and joyful beyond the daily realities of living with Multiple Sclerosis. A couple of weeks ago, I tried to buy tickets to see O.A.R. (among our favorite rock…
AAN2026. Barrier to treatment for Ocrelizumab
Tweet MS treatments are expensive and it is OK if you live in a place with Social Medicine but in many parts of the World one of the features that limits access to treatments is economics. It is scandalous that some countries penalise people for their health. This study looks at access to ocrelizumab and…
AAN226. Ocrelizumab and ADA. Is it too good to be true?
Tweet Anti-drug antibodies can stop drugs from working and can cause infusion reactions. They are rare to common occurrances due to the target the drug, the person, the assay, the reporting levels and the route. The subcutaneous route is under the skin and can induce more antibody responses than the intravenous (Infusion) route. However we…
There’s something about being left
I’m learning more and more about how the realities of my disabled life affect my psyche and leave me feeling traumatized. For many reasons, I am often left alone unplanned in very vulnerable positions. For example, during the day you’ll often find me sitting at me computer with my wheelchair turned off and my legs…