Tweet Are all anti-CD20 the same? They all target the the same molecule i.e. CD20 binding due to the front end of the antibody and all have the same basic back end (Human IgG1) and all of them deplete the memory B cells. However, how they do this is different. How they are used and…
New European patent covers all dosing regimens of experimental MS therapy
Immunic Therapeutics has been granted a new patent in Europe covering multiple dosing regimens of its experimental therapy vidofludimus calcium and related molecules for multiple sclerosis (MS) and other indications. The patent, titled “Dosage Regimen of Vidofludimus for Use in the Treatment of a Chronic Inflammatory and/or Autoimmune Diseases,” covers all relevant dosing regimens of…
My dysphagia from MS shows up during a difficult swallowing study
In the not-too-distant past, when my hands were still deft enough to use tools, I really enjoyed working on vehicles. The fact that they weren’t vehicles I depended on every day helped make it a hobby I enjoyed, rather than a chore. Like any hobby, it had its dull moments, but the only time it…
Brain volume loss may not reflect disability in progressive MS
Loss of brain volume (brain atrophy), a measure often used in clinical trials to track disease progression, may not accurately reflect worsening disability in people with primary progressive multiple sclerosis (PPMS). That’s according to a new analysis of data from the Phase 3 PROMISE trial, in which measures of brain atrophy were only poorly associated…
Along with hardships, my MS diagnosis has been a journey of learning
In recognition of Multiple Sclerosis Awareness Month in March, the MS Awareness Month campaign features a series of stories highlighting the real-life experiences of people affected by MS, written in their own words. Follow us on Facebook, Instagram, X, and Pinterest for more stories like this, using the hashtag #MSAwarenessMonth, or read the full series….
Trying Too Hard to Say Duh!
Tweet What’s Multiple Sclerosis? I was having a telecom with ProfK today and we we were talking about the blog not working and AI and information flow and ProfK said what do we say to people with MS and it is don’t smoke, exercise, eat healthy and use your brain, which is the general advice…
We are Back
Tweet Sorry about the delay….ProfK and I are abit backwards when it comes to certain technology. I got heavily into the internet many years ago and was one of the first people to get an email, which I got because I was working with a government supported lab. When the internet eventually came to the…
MS causing fewer deaths, less disability than in the past: Study
Although the total number of people living with multiple sclerosis (MS) has increased globally in recent decades due to population growth and aging, MS is causing fewer deaths and less disability now than in the past, according to a new study. Predictions also suggest that this trend toward reduced disease burden will likely continue in…
Living with MS migraines and navigating the ‘prior authorization’ trap
Dealing with multiple sclerosis (MS) — including the numerous symptoms that manifest differently for each person, the grief, and the uncertainty — is grueling. On top of all that, there’s the added challenge of navigating the American healthcare system. As I have written before, I’ve dealt with migraines since I was 13. They were often…
Briumvi outperforms Aubagio in highly active relapsing MS: Study
The CD20 inhibitor Briumvi (ublituximab) significantly outperformed Aubagio (teriflunomide) at lowering relapse rates and reducing disease activity on brain MRI scans in people with highly active relapsing forms of multiple sclerosis (MS). That’s according to a new analysis of pooled data from the ULTIMATE I (NCT03277261) and ULTIMATE II (NCT03277248) Phase 3 clinical studies, which…