What’s next in remyelination therapy? Remyelination substances currently under observation include the following (see Multiple Sclerosis Journal for details): New imaging technologies are under development to measure remyelination efficacy, including: diffusion tensor imaging (DTI) magnetized transfer imaging (MTI) myelin water fraction imaging (MWF) positron emission tomography (PET) The authors of “Remyelination in Multiple Sclerosis –…
Month: July 2019
Diet
In demyelinating diseases such as multiple sclerosis (MS), the failure to remyelinate contributes to axonal damage1, a major factor in persistent disability. Remyelination failure can be attributed partially to an insufficient capacity of resident oligodendrocyte precursor cells (OPC) to proliferate, migrate, differentiate and initiate myelin membrane growth2,3. There is now good evidence to implement therapies…
Repair of MS Brain Damage May be Possible
Repair Of Multiple Sclerosis Brain Damage May Be Possible Published Thursday 1 November 2012 By Catharine Paddock PhDIn what they describe to the press as a “life-changer” for millions of people with the disease, researchers in the US report this week a study where they discovered blocking an enzyme in the brain may help repair…
Brains Really Grow Back Neurons
The observation that the human brain churns out new neurons throughout life is one of the biggest neuroscience discoveries of the past 20 years. The idea has captured immense popular and scientific interest—not least, because of hopes the brain’s regenerative capacity might be harnessed to boost cognition or to treat injury or disease. In nonhuman…
Brain Tissue Regen
Can dead brain tissue regenerate?A new stroke-healing gel created by UCLA researchers helped regrow neurons and blood vessels in mice whose brains had been damaged by strokes. … Instead, dead brain tissue is absorbed, which leaves a cavity devoid of blood vessels, neurons or axons — the thin nerve fibers that project from neurons. Columbia neuroscientists have discovered why mitochondria, tiny…
Stimulating
A team led by University of Idaho scientists has found a way to stimulate formation of new neural connections in the adult brain in a study that could eventually help humans fend off memory loss, brain trauma and other ailments in the central nervous system. Peter G. Fuerst, an associate professor in the College of…
Electricity!
Manipulating myelin Australian researchers have found that the electrical activity of nerve cells in the brain plays an important role in the growth of myelin. This laboratory discovery may lead to new interventions to promote myelin repair in MS. Last updated: 15th February 2018 An Australian-led team of researchers have found that stimulating nerve cells…
Active Brain is Key
Active brain regions make more myelin Australian research probes the link between white matter and activity. Fiona McMillan reports. New research shows that increased electrical activity in an individual neuron leads to a thicker myelin coating around its axon, which can help speed up the transmission of neural signals. The study, published in Nature Communications, helps to…
Case Studies
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