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Month: December 2025

MS relapses peak in spring, summer as temperatures rise: Study

Posted on December 19, 2025 by

Relapses in people with relapsing-remitting multiple sclerosis (MS) may be more common in spring and summer, coinciding with warmer temperatures, low humidity, and greater fluctuations in atmospheric pressure, according to a study from Poland. Stressful life events and infections were the most frequent potential relapse triggers, the study found. “Better recognition of these issues within…

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Battle of the High Efficacy Agents…Is anti-CD20 depletion the bee’s knees compared to migration inhibition?

Posted on December 19, 2025 by

Tweet This paper potentially hasn’t been peer-reviewed and looks at the differences between natalizumab and ocrelizumab and does a virutal head to head with the conclusion that anti-CD20 is more effective than natalizumab on disability progression and concludes that ocrelizumab is better….So is this bad news for the anti-CD49d. However, currently in Europe, ocrelizumab can…

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Planning for life with MS means being willing to adapt

Posted on December 18, 2025 by

When I checked into the hospital last month, I answered all the usual diagnostic questions, but then one caught me off guard. A social worker asked if I had an advance directive in place. My first thought was to wonder just how bad the lab results were since I hadn’t seen them yet, but I…

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Antioxidant lipoic acid slows brain atrophy in progressive MS: Study

Posted on December 18, 2025 by

In people with progressive multiple sclerosis (MS), treatment with the antioxidant lipoic acid did not improve walking or lessen other symptoms, such as fatigue, but it did show signs of slowing brain atrophy, or the loss of brain tissue. According to the researchers, this suggests possible positive biological effects from the antioxidant’s use, despite no…

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Researchers identify enzyme as new target for MS myelin repair

Posted on December 18, 2025 by

An enzyme called CEMIP could be a target for small-molecule inhibitors that aim to promote myelin repair in people with multiple sclerosis (MS) and other conditions marked by myelin loss, a study found. Researchers discovered that CEMIP, which is elevated in areas of inflammatory nerve damage in people with MS, produces numerous hyaluronic acid molecules…

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Cladribine works because of effects of T regulatory cells–Yarn?

Posted on December 18, 2025 by

Tweet Immunologists are rather dogmatic and prescriptive and the mantra these days is that disease is driven by TH17 CD4 T cells and it is controled by T regulatory cells….I say Yarn because this is the current dogma and we get fed this idea over and over again. There are studies that look at T…

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Myelin damage scrambles brain communication, mouse study finds

Posted on December 17, 2025 by

Myelin, the protective coating that helps nerve signals travel quickly and efficiently, also plays a key role in the precise timing of communication between brain cells, a new study from scientists in the Netherlands shows. In a mouse model, the researchers found that the loss of myelin disrupted the coordination of signals between different brain…

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2025 Year in Review Through Bingo

Posted on December 17, 2025 by

By Stacie Prada December is the perfect time to reflect on how the past year measured up to hopes and goals. In January, I created a 2025 Bingo card that reflected various priorities I have. It proved useful and motivating … Continue reading → Source: blog.mymsaa.org

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Can music therapy make MS spasticity injections less painful?

Posted on December 17, 2025 by

A clinical trial testing whether music therapy can make botulinum toxin injections for spasticity more tolerable for people with multiple sclerosis (MS) and other neurological conditions is enrolling participants at Clermont-Ferrand University Hospital in France.  The study’s protocol was published in PLOS One, in a paper titled, “Musical intervention to reduce stress during botulinum toxin injection…

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Ramadan and MS

Posted on December 17, 2025 by

Tweet You can read the conclusions Nourmohammad A, Zorriyeh-Sheikhali M, Sanaie S, Naseri A. Ramadan fasting in multiple sclerosis: A systematic review. Mult Scler Relat Disord. 2025 Dec 8;106:106920. doi: 10.1016/j.msard.2025.106920. Epub ahead of print. PMID: 41389459. Background and aims: During Ramadan, the ninth month of the Islamic calendar, Muslims should abstain from eating, drinking, smoking,…

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