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Breakthrough Again

Posted on January 5, 2026 by
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I was asked what I thought of the MS in the media report.

“Two new subtypes of MS found in ‘exciting’ breakthrough…Scientists have discovered two new subtypes of  MS paving the way personalised treatments and better outcomes for patients”

I choose not to comment on these papers becuase of the agro it causes, but you know what I think about P for predict from imaging and neurofilament studies…they are good a suggesting what may happen at a population level but at the individual level I have not been impressed of the correlations…but here artifical intelligence can make a breakthrough of those with early neurofilament loss verse those with most likely hood of worsening or early deficit great.

This is the paper is “Willard C, Puglisi L, Ravi D, Dmitrieva M, Mattiesing RM, Barkhof F, Alexander DC, Harlow DE, Piani-Meier D, Eshaghi A. Combined magnetic resonance imaging and serum analysis reveals distinct multiple sclerosis types. Brain. 2025;148(12):4578-4591. doi: 10.1093/brain/awaf331. PMID: 41325776;

Source: multiple-sclerosis-research.org

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