Tweet Anti-drug antibodies can stop drugs from working and can cause infusion reactions. They are rare to common occurrances due to the target the drug, the person, the assay, the reporting levels and the route. The subcutaneous route is under the skin and can induce…
I’m learning more and more about how the realities of my disabled life affect my psyche and leave me feeling traumatized. For many reasons, I am often left alone unplanned in very vulnerable positions. For example, during the day you’ll often find me sitting at…
Tweet Yep the good news is that the EMA has approved the French Drug for progressive MS. This a Brutons Tyrosine kinase inhibitor that the FDA pushed back on. Will this arrive and make it past NICE in the UK well it has to be…
It’s the last day of MS Awareness Week with the campaign of #MSThinkAgain, which has been challenging all the assumptions that surround the condition, which just aren’t true. Every day this week, Dizzy and I have been considering the misconceptions we have encountered, and…
By Samuel Fitch There comes a point where continuing the same patterns will only lead you further away from the life you actually want to live. For me, that moment wasn’t dramatic. It was quiet, but undeniable. Between living with … Continue reading → Source:…
Ocrevus (ocrelizumab) delayed disability progression and worsening hand function among a large group of people with primary progressive multiple sclerosis (PPMS), including those who were older and had more advanced disease. The data, which come from the Phase 3 ORATORIO-HAND trial (NCT04035005), were presented by…
Tweet I have been critical of neuros for using the escalating apporach to DMT and you us a higher efficacy drug after the failure of treatment. A strategy based on failure was always a flawed approach and you paid the price for reluctance of neuros/nurses…
Tweet Recently we were talking about the hare and the tortoise and the first hares related to bruton tyrosine kinase irreversible inhibitors failed to beat teriflunomide in trials in relapsing MS. We then heard an reversible inhibitor was active and at that point I asked…
When I began this column about living with multiple sclerosis (MS) nearly four years ago, I worried about sharing good things in my life and about comparing my situation with that of others. It made me feel guilty. After writing about it, though, the feedback…
If I sit for over three minutes, it takes almost that long to regain movement in my legs when I stand. Even then, my limbs must fight the relentless pressure of immobility. Focused therapies, such as the Portable Neuromodulation Stimulator, have given me back years…