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It’s WorldMSDay again, and…

Tweet …there’s plenty of declarations of good will, compassion, energy to solve problems related to MS – that’s all great and laudable. However, I can’t stop thinking there are some elephants in the room that keep getting ignored since people tend to jump on the…

PIRA, PIRMA, RAW, MAW is it SH1-In, SH1-Out? We need to target different processes to those targeting relapses to limit disability progression

Tweet Tur C. High-efficacy therapy and progression independent of relapse and MRI activity in multiple sclerosis. Brain. 2026:awag175. https://doi.org/10.1093/brain/awag175 They say “The main mechanism through which patients with multiple sclerosis (MS) acquire disability is progression independent of relapse activity (PIRA)” (Yep a widely held view)…..”However,…