At a recent social gathering, my military career came up, including the more than 100 parachute jumps I’ve done in my life. As usual, someone remarked that I must have […] The post When it comes to fight or flight, MS has made me flightless…
TG Therapeutics has started enrolling participants in a Phase 3 trial to test a new version of Briumvi (ublituximab-xiiy) that can be injected at home. This change could offer greater […] The post Phase 3 trial begins for at-home injectable version of Briumvi appeared first…
Immunic Therapeutics will receive a new U.S. patent covering its experimental therapy, vidofludimus calcium, and some related molecules in people with multiple sclerosis (MS). Titled “Treatment of multiple sclerosis comprising DHODH inhibitors,” […] The post New patent covers progressive MS drug for patients in US appeared first…
Tweet This week we had the suggestion that there were more infections in people treated with rituximab than oreclizumab, I suggested that there wre differences in the way that rituximab kill B cells and I also suggested that people got a third more rituximab than…
We all have stomach or bathroom issues from time to time. Eat the wrong thing, catch a bug, drink too much coffee, and your body will let you know. That’s […] The post Guest Voice: Dealing with digestive and urinary problems in MS appeared first…
By Samuel Fitch When we think of the word reset, we often picture restarting a computer or a phone. Most problems on a device can be fixed with a simple restart. But when it comes to us—our physical, human selves—we don’t … Continue reading → Source:…
Tweet Know one you know them all? Are the CD20-depleting antibodies all the same?. You would think so, as they all deplete CD20 positive B cells but this study says that rituximab causes more infections than ocrelizumab. The weird thing is other people are saying…
Tweet It was demanded that I post as many EAE and Mouse posts as possible from ECTRIMS2025… so happy to oblige. The first post from ECTRIMS2025 is about anti-CD40 ligand this blocks T cells interacting with B cells to deliver their activating signal. However a…
Tweet It was demanded that I post as many EAE and Mouse posts as possible from ECTRIMS2025… so happy to oblige. The first post from ECTRIMS2025 is about anti-CD40 ligand this blocks T cells interacting with B cells to deliver their activating signal. However a…
Tweet Next up ….Especially for the Requester..Re-inventing a mouse model of EAE…..here we take a mouse that is is essentially empty of mouse T and B cells so we can fill it full of human cells and here they make MOG-reactive CAR-T cells and it…