Closely following a Mediterranean diet — which involves eating lots of fruits, vegetables, and whole grains, and limiting intake of processed and sugary foods — is associated with a significantly lower risk of developing multiple sclerosis (MS), a large Swedish study has found. The benefits,…
Tweet We all want to monitor progression and many years ago it was suggested that TSPO is a marker of activated microglia and we have a large number of imaging studies claiming that using TSPO imaging we can see activated microglia in MS. We however…
Tweet Bruno PA, Barone S, Pascarella A, Lanza PL, Tinelli E, Gambardella A, Valentino P. B-cell-driven relapse and anti-CD20 rescue therapy after Alemtuzumab in RRMS: case report and literature review. Front Immunol. 2026;16:1710669. Background: Alemtuzumab is an immune reconstitution therapy (IRT) approved for highly active relapsing-remitting…
Today marks nine days since Dan’s hernia surgery. From my perspective, he is healing like a champ. Each day he is a little steadier, a little stronger, and a little more himself. His pain is easing and watching his body recover has been a genuine…
Tweet Yesterday we had CD20-depleting antibodies switch after alemtuzumab works well and today it is a switch from fingolimod. Fingolimod is a strange drug because it hangs around a long time and when the drug wears of there is the potential for relapse = rebound…
At 50, I’m realizing there are a lot of things I’ve stopped doing: nightclubs, late nights, obsessing over my hair, changing my outfit three times before leaving the house, staring at my phone waiting for a boy to call, and caring way too much about…
Happy Friday to an amazing group of people whose thoughts I value. I hope you have been doing well. I know it has been a while since my last post, but sometimes life struggles get in the way of writing, especially when it comes to…
For people with multiple sclerosis (MS), difficulty walking is not just about physical limitations. It is also shaped by emotions, social interactions, and how easily people can take part in everyday life, a review study found. The findings highlight the many factors that can negatively…
Tweet There has been lot of discussion about reference (originator) natalizumab and biosimilar natalizumab and some people have been claiming that the biosimilar, after they were switched, does not work as well and they have been quite vocal causing some places to switch back. This…