×

For young nonsmokers, following Mediterranean diet may slash MS risk

Closely following a Mediterranean diet — which involves eating lots of fruits, vegetables, and whole grains, and limiting intake of processed and sugary foods — is associated with a significantly lower risk of developing multiple sclerosis (MS), a large Swedish study has found. The benefits,…

Imaging Hot Microglia?

Tweet We all want to monitor progression and many years ago it was suggested that TSPO is a marker of activated microglia and we have a large number of imaging studies claiming that using TSPO imaging we can see activated microglia in MS. We however…

anti-CD20 saving alemtuzumab failure

Tweet Bruno PA, Barone S, Pascarella A, Lanza PL, Tinelli E, Gambardella A, Valentino P. B-cell-driven relapse and anti-CD20 rescue therapy after Alemtuzumab in RRMS: case report and literature review. Front Immunol. 2026;16:1710669.  Background: Alemtuzumab is an immune reconstitution therapy (IRT) approved for highly active relapsing-remitting…

Dan’s healing: The weeks after surgery

Today marks nine days since Dan’s hernia surgery. From my perspective, he is healing like a champ. Each day he is a little steadier, a little stronger, and a little more himself. His pain is easing and watching his body recover has been a genuine…

The switching option after fingolimod?

Tweet Yesterday we had CD20-depleting antibodies switch after alemtuzumab works well and today it is a switch from fingolimod. Fingolimod is a strange drug because it hangs around a long time and when the drug wears of there is the potential for relapse = rebound…

❄️Done With ICE!🧊

Happy Friday to an amazing group of people whose thoughts I value. I hope you have been doing well. I know it has been a while since my last post, but sometimes life struggles get in the way of writing, especially when it comes to…