Tweet Depleting antibodies work because they deplete. So check white blood cells and they drop. Natalizumab keeps cells out of the brain and so white blood cells will increase lymphocytes go up by an average of 1.8 x 10*9 cells per litre but on the whole they stay within the normal range 1 to 4.9–4.5…
Category: Multiple Sclerosis Research
MS subtypes
Tweet Historically we have defined MS as relapsing and progressive but in the time of Boys with Toys and artificial intelligence there are moves to define MS Subtypes and this on using biomarkers in the form of neurofilament (NfL) as a marker of nerve damage and magnetic resonance imaging Brummer T, Fleischer V. Beyond clinical…
switching from cladribine
Tweet This says it is possible to switch and get activity….I guess the question why the failure? Disease activity was the reason for switch. However, no agent is 100% effective. Also what is the reason for failure? Anti-drug antibodies could mean it has stoppped working but tests are seldom available Konen FF, Pfeuffer S, Jendretzky…
Collaboration will make MSDA blood test easier to access in US
Octave Bioscience is entering into a collaboration with Quest Diagnostics to expand access to its multiple sclerosis disease activity (MSDA) test, which uses data from a set of blood biomarkers to measure how active a patient’s disease is in people with multiple sclerosis (MS). Although the MSDA test became widely available across the U.S. earlier…
🐱Life With Cats😽
Happy Friday, y’all! I hope you have had a good week and that you are looking forward to a relaxing weekend. The weather where I live has remained cold and rainy, but I can appreciate the cold weather. Normally, I have done let it go Friday posts, but this post is going to be a…
Progressing Through Heartache
By Samuel Fitch As I write this on December 1, 2025, my mind turns to the year behind me. The first thought that rises is the people we lost. My mother passed away extremely unexpectedly on June 9. Her absence … Continue reading → Source: blog.mymsaa.org
Could a daily coffee habit lower MS risk? New analysis says yes.
People who drink coffee may have a more than 20% lower risk of developing multiple sclerosis (MS) compared with those who do not, according to a new analysis of published studies that pooled data from more than 4,500 participants from seven countries. “These results suggest that coffee consumption might have a protective effect against MS,…
The future becomes the present with a recent bout of pneumonia
I mentioned last week that I had been in the hospital recently with pneumonia and promised to elaborate. Without further ado or any gross details, I give you my recent tale of woe. As with many of my experiences, may it serve as a warning of what not to do. Like most people, I don’t…
FDA clears clinical trials for Lynk’s oral MS therapy
Lynk Pharmaceuticals has received the green light from the U.S. Food and Drug Administration (FDA) to begin clinical trials of its investigational oral therapy LNK01006, which is being developed for multiple sclerosis (MS) and other neuroinflammatory diseases. “We look forward to advancing this promising molecule into human clinical trials and bringing new therapeutic options to…
Cladribine to the rescue of the Gut
Tweet Co-morbidities are a feature of age..as you get older you slowly get all sorts of other conditions….I once went to some student presentations were students have to present on current and future treatments for a condition they had selected autoimmune hepatitis because their mother had it. My heart bled when they said they got…