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Crap Gap

Tweet I was at a meeting recently and they started talking about the wearing -off effect…some people piped up that it was all in the minds of some people and that when you do a proper controlled study as opposed to listening to Mr/Mrs Big…

Let It Go Friday

Happy Friday, y’all! I hope you have had a great week and that you are looking forward to a lovely weekend! During this past week, what was your best day and why was it your best day? Was there anything that happened during your week that upset…

New method shines light on nerve fibers in the brain

A new technique is letting scientists peer into the brain’s wiring with greater detail by simply using a microscope and an LED light, an accessible and cost-effective method that may be useful for studying brain damage in neurological diseases such as multiple sclerosis (MS). The…

What a difference a day makes

Tweet Before yesterday people may have got away with the punch line “These findings suggest that the association of EBV and MS is specific for MS” This implies there is something very specific for MS and EBV…However this is clearly not true. Yesterday there were…

EBV and Autoimmunity…it’s not just MS

Tweet Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus. Younis S, Moutusy SI, Rasouli S, Jahanbani S, Pandit M, Wu X, Acharya S, Sharpe O, Wijeratne TU, Harris ML, Yang EY, Chaichian Y, Parsafar S, Baker MC, Harley JB, Meffre…

MS drug fenebrutinib shows ‘unprecedented results’ in trials

Genentech‘s experimental oral therapy fenebrutinib has become the first Bruton’s tyrosine kinase (BTK) inhibitor to show positive Phase 3 results in both relapsing forms of multiple sclerosis (MS) and primary progressive MS (PPMS), the company announced. In what Genentech called “unprecedented results,” two late-stage trials…

Wearable sensors move MS brain imaging beyond MRI machines

A new wearable brain-mapping tool could dramatically change how doctors monitor people with multiple sclerosis (MS), making it easier to track disease progression and guide personalized care. Researchers showed the system, OPM-MEG, reliably detects abnormalities in the brain’s electrical activity in MS patients. The portable…