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Cranberry Orange Relish

Thanksgiving tables are full of rich, comforting dishes and this Cranberry Orange Relish brings the perfect balance with its fresh, zesty pop of flavor. It’s a no-cook recipe that celebrates cranberries natural tartness while adding a citrusy lift from fresh … Continue reading → Source:…

Anti-Drug Antibodies

Tweet Infusion reactions can occur as a consequence of different things but one potential is an allergic reaction due to anti-drug antibodies. Now you have been told they are rare and it is often implied that they are unimportant. Whilst at the population level, this…

Surviving Life

Happy Tuesday, y’all! I hope you have been doing well and taking everything that life throws your way in stride. The truth is, we do not have a choice but to try to handle the struggles in life the best we can.  I know it…

Why am I still stuck on the new McDonald criteria?

Tweet The new 2024 revisions to the McDonald criteria for the diagnosis of MS have significantly changed the way we view the condition. Beyond the general confusion caused by not everyone remembering all the points of the criteria, one area I still find difficult to…

$2.5M gift goes to Case Western team to advance MS research

Scientists at Case Western Reserve University (CWRU) in Ohio will use a new $2.5 million donation from the Thomas F. Peterson Jr. Charitable Trust to develop therapeutic strategies for multiple […] The post $2.5M gift goes to Case Western team to advance MS research appeared…

Safe to Switch

Tweet There are five different anti-CD20 used in MS (rituximab-Off label), divozilimab (Russia), ublituximab, ocrelizumab, ofatumumab which bind to 4 different and 3 more markedly different targets on CD20, so if you fail one you can switch to another. The current most common is ocrelizumab…

Caregiver challenges are killing me

As a fiercely independent person it kills me that I have to rely on caregivers for my most basic needs but it’s a reality I’ve had to learn to accept. Without these folks, I can’t function. My reality is that I require 24/7 care. My…

Its all in the Gut?

Tweet Myelin reactive T cells that have a receptors that target myelin have all they need to cause autoimmunity, all that is needed is for the cells to be activated to get into the CNS and cause disease. Here bacteriua in the smal, intesting of…

EBV and antibodies

Tweet A few years ago a couple of papers appearred that sent the MS World EBV mad and it awakened the idea that Epstein Barr Virus is in the causal pathway of MS. It was then suggested that antibodies to EBV cross react with glial…